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PTGER2

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For Research Use Only. Not For Clinical Use.


Background

This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma.
Protein class

FDA approved drug targets, G-protein coupled receptors, Human disease related genes

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (NK-cells, T-cells, dendritic cells, Macrophages)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (ASC diff, ASC TERT1, HHSteC, HL-60, HSkMC)

Molecular function

G-protein coupled receptor, Receptor, Transducer

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