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PTPA
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B.
Protein class
Enzymes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Ductal cells, Exocrine glandular cells, Pancreatic endocrine cells, Distal tubular cells, Hofbauer cells, Collecting duct cells, Breast glandular cells, Cytotrophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Associates with PP2A heterodimeric core enzyme PP2A(D), composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A) (PubMed:16916641). Interacts with PPP2CB (By similarity).
Molecular function
Isomerase, Rotamase
More Types Infomation
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA
- Mouse Anti-PTPA Recombinant Antibody (clone 4D9) (VS3-XY1320)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC, IHC, ICC
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For Research Use Only. Not For Clinical Use.