PvDBPII
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Loading...- Human Anti-PvDBPII Antibody (PABJ-0070-mRNA), mRNA (PABJ-0070-mRNA)
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- Species Reactivity: P. vivax
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- Human Anti-PvDBPII Recombinant Antibody (clone DB1) (VS-0423-XY15)
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- Species Reactivity: Plasmodium vivax
- Type: Human IgG
- Application: ELISA
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- Human Anti-PvDBPII Recombinant Antibody (clone DB2) (VS-0423-XY16)
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- Species Reactivity: Plasmodium vivax
- Type: Human IgG
- Application: ELISA
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- Human Anti-PvDBPII Recombinant Antibody (clone DB3) (VS-0423-XY17)
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- Species Reactivity: Plasmodium vivax
- Type: Human IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
Background
PvDBP has been divided into six distinct regions, with the DARC binding site mapped to a ~350 amino acid residue Duffy-binding-like (DBL) domain known as Region II, PvDBPII6. This domain is split into three regions, known as subdomains 1-3 5. PvDBPII binds to the sixty-residue extracellular N-terminal ectodomain of DARC, in an interaction which requires DARC to be post-translationally modified by sulphation of two tyrosine residues, Tyr30 and Tyr41.