Metabolic proteins, Plasma proteins, Transporters
Intracellular
Cell type enhanced (Spermatocytes, Early spermatids)
Low immune cell specificity
Low cell line specificity
Interacts with NUMA1 (via N-terminal end of the coiled-coil domain); this interaction promotes spindle formation in mitosis (PubMed:17172455). Interacts with NUP98 (PubMed:20498086). Interacts with MYCBP2 (PubMed:22357847). Interacts with USP11 (PubMed:29293652). (Microbial infection) Interacts with SARS coronavirus-2/SARS-CoV-2 ORF6 protein; the interaction displaces RAE1 from the nuclear envelope and impairs its role in nucleocytoplasmic transport. (Microbial infection) Interacts with SARS coronavirus/SARS-CoV ORF6 protein.
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For Research Use Only. Not For Clinical Use.