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For Research Use Only. Not For Clinical Use.
Intracellular, Membrane (different isoforms)
Cell type enhanced (Squamous epithelial cells, Respiratory ciliated cells, Basal respiratory cells, Early spermatids, Suprabasal keratinocytes, Late spermatids)
Not detected in immune cells
Cell line enhanced (HBEC3-KT, HeLa, hTCEpi, SiHa, U-87 MG)
Binds to KLRK1/NKG2D. (Microbial infection) Contrary to other family members, does not interact with CMV glycoprotein UL16.