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RHOBTB1
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Horizontal cells, Syncytiotrophoblasts, Oligodendrocytes, Cone photoreceptor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (Hep G2)
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