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For Research Use Only. Not For Clinical Use.
Disease related genes, Human disease related genes
Intracellular
Cell type enhanced (Oligodendrocyte precursor cells, Oligodendrocytes, Astrocytes, Microglial cells)
Immune cell enhanced (classical monocyte)
Cell line enhanced (PC-3)
Homotetramer; probably composed of anti-parallel linkage of two parallel dimers. Interacts with Ras. Interacts with RAB5B, with a much higher affinity for GTP-bound activated RAB5B. Does not interact with other members of the Rab family.
GTPase activation