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RNF213
Loading...Anti-RNF213 Products
- Recombinant Mouse Anti-Human RNF213 Antibody (MOB-0963MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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- Anti-RNF213 Immunohistochemistry Kit (VS-0325-XY1931)
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- Species Reactivity: Human, Mouse
- Target: RNF213
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Protein class
Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (NK-cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HDLM-2)
Interaction
Monomer (By similarity). Interacts with UBE2L3/UBCH7; UBE2L3/UBCH7 is the most efficient ubiquitin-conjugating enzyme E2 for the ubiquitin ligase activity (By similarity). Interacts with UBE2N/UBC13; promoting 'Lys-63'-linked ubiquitination of target proteins (PubMed:32139119, PubMed:33842849). (Microbial infection) Interacts with M. tuberculosis protein Rv3655c, which impairs caspase-8 activation and suppresses macrophage apoptosis by blocking the extrinsic pathway.
Molecular function
Hydrolase, Transferase
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