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ROM1
Anti-ROM1 Recombinant Antibody Products
- Recombinant Anti-Human ROM1 Antibody (MOB-1752z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, ELISA, IHC, FuncS
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- Recombinant Anti-Human ROM1 Antibody scFv Fragment (MOB-1752z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IF, FuncS
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For Research Use Only. Not For Clinical Use.
This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa.
Protein class
Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enriched (Rod photoreceptor cells)
Immune cell specificity
Immune cell enhanced (NK-cell)
Cell line specificity
Cell line enhanced (HSkMC, U-266/84)
Interaction
Homodimer; disulfide-linked (PubMed:1610568). Forms a homotetramer (By similarity). Forms a heterotetramer with PRPH2 (By similarity). Homotetramer and heterotetramer core complexes go on to form higher order complexes by formation of intermolecular disulfide bonds (By similarity). Interacts with STX3 (By similarity). Interacts with SNAP25 (By similarity).
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