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RTKN

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For Research Use Only. Not For Clinical Use.


Background

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Group enriched (plasmacytoid DC, NK-cell)

Cell line specificity

Cell line enhanced (Hep G2)

Interaction

Interacts via its C-terminal region with the TAX1BP3 PDZ domain. This interaction facilitates Rho-mediated activation of the c-Fos serum response element (SRE). Interacts with SEPT9. Specifically binds to GTP-bound RHOA, RHOB and RHOC and inhibits their GTPase activity.

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