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Gene
RTN1

RTN1

Engineered Antibody

This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]

Protein class

Plasma proteins, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Excitatory neurons, Inhibitory neurons, Oligodendrocytes, Horizontal cells, Oligodendrocyte precursor cells)

Immune cell specificity

Group enriched (myeloid DC, intermediate monocyte, classical monocyte)

Cell line specificity

Group enriched (HEL, SCLC-21H, SH-SY5Y)

Interaction

Interacts with NDRG1 (PubMed:15922294). Interacts with BACE1 (PubMed:15286784). [Isoform RTN1-A]: Interacts with TMEM33 (PubMed:25612671). [Isoform RTN1-C]: Interacts with UGCG; regulates the ceramide glucosyltransferase activity of UGCG (PubMed:12873973).

More Types Infomation

Mouse Anti-RTN1 Recombinant Antibody (clone 36D4) (MOB-2879z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, ICC, IF, IHC

Mouse Anti-RTN1 Recombinant Antibody (clone RNL-4) (ZG-1097F)
- Species Reactivity: Human, Rat, Pig
- Type: Mouse IgG1
- Application: FC, ICC, IHC-Fr, WB

Mouse Anti-RTN1 Recombinant Antibody (clone RNL-3) (ZG-1096F)
- Species Reactivity: Human, Monkey, Rabbit
- Type: Mouse IgG1
- Application: FC, ICC, IHC-Fr, IHC-P, WB

Mouse Anti-RTN1 Recombinant Antibody (clone RNL-2) (ZG-1095F)
- Species Reactivity: Human, Monkey, Rabbit
- Type: Mouse IgG1
- Application: FC, ICC, IHC-Fr, IHC-P, WB

Mouse Anti-RTN1 Recombinant Antibody (clone MON162) (ZG-1056F)
- Species Reactivity: Hamster, Human, Mouse, Rat
- Type: Mouse IgG1
- Application: ICC, IHC-Fr, IHC-P, WB

Mouse Anti-RTN1 Recombinant Antibody (clone MON161) (ZG-1055F)
- Species Reactivity: Hamster, Human, Mouse, Rat
- Type: Mouse IgG1
- Application: FC, ICC, IHC-Fr, IHC-P, WB

Mouse Anti-RTN1 Recombinant Antibody (clone MON160) (ZG-1054F)
- Species Reactivity: Hamster, Human, Mouse, Rat
- Type: Mouse IgG1
- Application: FC, ICC, IHC-Fr, IHC-P, WB

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