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Rab6
Loading...Anti-Rab6 Products
- Recombinant Anti-Rab6 Antibody (MOB-836)
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- Derivation: Mouse
- Type: IgG
- Application: WB, ELISA, IHC, FuncS
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- Recombinant Human Anti-Rab6 Antibody (MHH-836)
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- Derivation: Human
- Type: IgG
- Application: ELISA, IP, FuncS
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- Recombinant Human Anti-Rab6 Antibody Fab Fragment (MHH-836-F(E))
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- Derivation: Human
- Type: Fab
- Application: WB, FuncS
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- Recombinant Human Anti-Rab6 Antibody scFv Fragment (MHH-836-S(P))
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- Derivation: Human
- Type: scFv
- Application: WB, IP, FuncS
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- Recombinant Anti-Rab6 Antibody Fab Fragment (MOB-836-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: FC, WB, FuncS
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- Recombinant Anti-Rab6 Antibody scFv Fragment (MOB-836-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: WB, FC, FuncS
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For Research Use Only. Not For Clinical Use.
Recombinant antibodies specific to the guanosine triphosphate (GTP)-bound conformation of the small guanosine triphosphatase (GTPase) Rab6, a regulator of membrane traffic, were generated and used to locate Rab6.GTP in fixed cells, and, after green fluorescent protein (GFP) tagging and intracellular expression, to follow Rab6.GTP in vivo. Rab6 was in its GTP-bound conformation on the Golgi apparatus and transport intermediates, and the geometry of transport intermediates was modulated by Rab6 activity. More generally, the same approach could be applied to other molecules that can be locked in a particular conformation in vitro.