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SAGE1

Anti-SAGE1 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, ELISA
- Rabbit Anti-Human SAGE1 Antibody (FITC) (MOB-0348MC)
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- Species Reactivity: Human
- Application: IF/ICC
- Rabbit Anti-SAGE1 Recombinant Antibody (VS13-YC1035) (VS13-YC1035)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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For Research Use Only. Not For Clinical Use.
Background
This gene belongs to a class of genes that are activated in tumors. These genes are expressed in tumors of different histologic types but not in normal tissues, except for spermatogenic cells and, for some, placenta. The proteins encoded by these genes appear to be strictly tumor specific, and hence may be excellent sources of antigens for cancer immunotherapy. This gene is expressed in sarcomas.
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Spermatogonia)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AN3-CA, K-562, Karpas-707, U-2 OS, U-266/70, U-266/84)
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