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SLC17A7

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For Research Use Only. Not For Clinical Use.


Enables L-glutamate uniporter activity and inorganic anion transmembrane transporter activity. Involved in several processes, including L-glutamate transmembrane transport; neurotransmitter loading into synaptic vesicle; and phosphate ion transport. Acts upstream of or within several processes, including chemical synaptic transmission; long-term memory; and sequestering of neurotransmitter. Located in several cellular components, including cerebellar mossy fiber; presynaptic active zone; and synaptic vesicle membrane. Is expressed in several structures, including brain; retina layer; and spinal cord dorsal horn. Orthologous to human SLC17A7 (solute carrier family 17 member 7).
Protein class

Metabolic proteins, Transporters

Predicted location

Membrane

Single cell type specificity

Group enriched (Cone photoreceptor cells, Bipolar cells, Rod photoreceptor cells, Excitatory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HMC-1, K-562, REH, SCLC-21H)

Interaction

Interacts with SHANK3.

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