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SLU7

Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions.
Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Component of pre-catalytic, catalytic and post-catalytic spliceosomes (PubMed:10197984, PubMed:28502770, PubMed:30705154). Associates with the spliceosome prior to recognition of the 3'-splice site for step II, probably during catalysis of step I (PubMed:10197984).

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