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SMPD3

Anti-SMPD3 Products

Mouse Anti-SMPD3 Recombinant Antibody (clone 44B4) (MOB-3580z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, IP, IF, IHC, ELISA
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For Research Use Only. Not For Clinical Use.

Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.

Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Horizontal cells, Proximal enterocytes, dendritic cells, Gastric mucus-secreting cells)

Immune cell specificity

Immune cell enriched (plasmacytoid DC)

Cell line specificity

Cell line enhanced (HMC-1, MOLT-4, RPMI-8226, SCLC-21H)

Molecular function

Developmental protein, Hydrolase

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