Plasma proteins
Intracellular
Cell type enhanced (Muller glia cells, Excitatory neurons, Rod photoreceptor cells)
Low immune cell specificity
Cell line enhanced (SiHa)
Monomer and homodimer (Probable). Interacts with the other members of the syntrophin family: SNTA1 and SNTB1; and with the sodium channel proteins SCN4A and SCN5A. Interacts with SAST, MAST205, microtubules and microtubule-associated proteins (By similarity). Interacts with the dystrophin protein DMD and related proteins DTNA and UTRN, and with the neuroregulin receptor ERBB4. Interacts with PTPRN when phosphorylated, protecting PTPRN from protein cleavage by CAPN1. Dephosphorylation upon insulin stimulation disrupts the interaction with PTPRN and results in the cleavage of PTPRN. Interacts with DTNB (By similarity).
Actin-binding, Calmodulin-binding
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For Research Use Only. Not For Clinical Use.