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SNV Gn

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For Research Use Only. Not For Clinical Use.


Background

Sin Nombre virus (SNV) is a rodent-borne virus that can cause severe respiratory failure and death upon spillover from their reservoir host into humans. The hantavirus integral membrane surface glycoproteins, designated Gn and Gc, form hetero-oligomeric complexes on the virion surface containing four copies of each glycoprotein. These complex spikes facilitate viral attachment and fusion with the host-cell membrane.
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