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SOAT1
The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene.
Protein class
Enzymes, FDA approved drug targets, Metabolic proteins
Predicted location
Membrane
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homotetramer; composed of two homodimers (PubMed:32433614, PubMed:32433613). Interacts with UBIAD1 (PubMed:23169578).
Molecular function
Acyltransferase, Transferase
More Types Infomation
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, IHC-P, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ICC/IF, IHC-P, IP, WB
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For Research Use Only. Not For Clinical Use.