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SOX18
Loading...Anti-SOX18 Products
- Rabbit Anti-SOX18 Recombinant Antibody (VS13-YC1097) (VS13-YC1097)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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- Anti-SOX18 Immunohistochemistry Kit (VS-0525-XY6820)
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- Species Reactivity: Human
- Target: SOX18
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
Protein class
Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Group enriched (Adipocytes, Hepatic stellate cells, Endothelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HUVEC TERT2, NB-4, REH, TIME)
Interaction
Interacts (via C-terminus) with MEF2C (via MADS box).
Molecular function
Activator, DNA-binding
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