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SPR

Anti-SPR Products

Recombinant Mouse anti-Human SPR Monoclonal antibody (3G8) (MOB-1671CT)
- Species Reactivity: Human
- Application: WB
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Mouse Anti-NHP SPR Recombinant Antibody (clone OTI1F4) (VS-1024-XY491)
- Species Reactivity: Human, Non-human primate
- Type: Mouse IgG1
- Application: WB, IF, FC
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Anti-SPR Immunohistochemistry Kit (VS-0525-XY6868)
- Species Reactivity: Human
- Target: SPR
- Application: IHC
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Anti-Rat SPR Immunohistochemistry Kit (VS-0525-XY6869)
- Species Reactivity: Human, Rat
- Target: SPR
- Application: IHC
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Hi-Affi™ Recombinant Rabbit Anti-SPR Monoclonal Antibody (DS3395AB) (MOR-3395)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.

This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Proximal tubular cells, Distal enterocytes, Exocrine glandular cells)

Immune cell specificity

Group enriched (myeloid DC, classical monocyte, intermediate monocyte)

Cell line specificity

Low cell line specificity

Interaction

Homodimer.

Molecular function

Oxidoreductase

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