Disease related genes
Intracellular
Cell type enhanced (Early spermatids, Oligodendrocyte precursor cells, Astrocytes, Microglial cells, Muller glia cells, Oligodendrocytes)
Not detected in immune cells
Cell line enhanced (fHDF/TERT166, hTERT-HME1)
Homodimer (Probable). Forms a heterooligomer with SRGAP2 and SRGAP3 through its F-BAR domain. Interacts with ROBO1, CDC42 and RHOA. Interacts with FASLG.
GTPase activation
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For Research Use Only. Not For Clinical Use.