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SSR1

Anti-SSR1 Products
- Recombinant Mouse Anti-Human SSR1 Antibody (MOB-1437MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
- Anti-SSR1 Immunohistochemistry Kit (VS-0525-XY6919)
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- Species Reactivity: Human
- Target: SSR1
- Application: IHC
- Anti-Mouse SSR1 Immunohistochemistry Kit (VS-0525-XY6920)
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- Species Reactivity: Human, Mouse, Rat, Canine, Monkey
- Target: SSR1
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene.
Predicted location
Membrane
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma. Interacts with palmitoylated calnexin (CALX), the interaction is required for efficient folding of glycosylated proteins.
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