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ST6GALNAC4
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Erythroid cells, Plasma cells, Enteroendocrine cells)
Immune cell specificity
Immune cell enriched (plasmacytoid DC)
Cell line specificity
Cell line enhanced (HDLM-2, RPMI-8226)
Molecular function
Glycosyltransferase, Transferase
More Types Infomation
- Recombinant Anti-Human ST6GALNAC4 Antibody scFv Fragment (MOB-3856z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: IP, IF, Biosensors, FuncS
- Recombinant Anti-Human ST6GALNAC4 Antibody Fab Fragment (MOB-3856z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, RIA, FuncS
- Recombinant Anti-Human ST6GALNAC4 Antibody (MOB-3856z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, ELISA, IHC, FuncS
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For Research Use Only. Not For Clinical Use.