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For Research Use Only. Not For Clinical Use.
Cancer-related genes, Plasma proteins
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Part of the core SMN complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8 and STRAP/UNRIP (PubMed:16159890, 15848170, 17178713). Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG (PubMed:18984161). Associates with the SMN complex in the cytoplasm but not in the nucleus (PubMed:16159890). Interacts with GEMIN6; the interaction is direct (PubMed:15848170). Interacts with GEMIN7; the interaction is direct (PubMed:15848170, 17178713). Interacts with CSDE1/UNR and MAWBP (PubMed:10049359). Interacts with PDPK1 (PubMed:16251192). Interacts with TRIM48 (PubMed:29186683).