SUDS3

Recombinant Antibody Products

Anti-SUDS3 Recombinant Antibody Products

Hi-Affi™ Recombinant Rabbit Anti-SUDS3 Monoclonal Antibody (DS3457AB) (MOR-3457)
- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, FC
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For Research Use Only. Not For Clinical Use.

SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex.

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Early spermatids)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Homodimer. Component of the SIN3 histone deacetylase (HDAC) corepressor complex. Interacts with SIN3A. Interaction with SIN3B enhances the interaction between SIN3B and HDAC1 to form a complex (By similarity). Interacts with HCFC1. Component of a mSin3A corepressor complex that contains SIN3A, SAP130, SUDS3/SAP45, ARID4B/SAP180, HDAC1 and HDAC2. Interacts with USP17L2; the interaction is direct. Interacts with FOXK2 (PubMed:25805136).

Molecular function

Chromatin regulator, Repressor

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