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SULF1

Anti-SULF1 Products
- Recombinant Anti-Human SULF1 Antibody (MOB-2920z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, FC, FuncS
- Recombinant Anti-Human SULF1 Antibody Fab Fragment (MOB-2920z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, WB, FuncS
- Recombinant Anti-Human SULF1 Antibody scFv Fragment (MOB-2920z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, IP, FuncS
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For Research Use Only. Not For Clinical Use.
This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Early spermatids, Muller glia cells, Late spermatids, Inhibitory neurons, Fibroblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BJ, BJ hTERT+, fHDF/TERT166, U-2197, WM-115)
Molecular function
Hydrolase
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