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TFAP4

Anti-TFAP4 Products
- Chicken Anti-TFAP4 Polyclonal IgY (BRD-0584MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC-P, WB
- Anti-TFAP4 Immunohistochemistry Kit (VS-0525-XY7185)
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- Species Reactivity: Human
- Target: TFAP4
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG.
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Basal squamous epithelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Low cell line specificity
Interaction
Efficient DNA binding requires dimerization with another bHLH protein. Homodimer.
Molecular function
Activator, DNA-binding
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