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TFAP4

Anti-TFAP4 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG.
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Proximal enterocytes, Basal squamous epithelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Low cell line specificity

Interaction

Efficient DNA binding requires dimerization with another bHLH protein. Homodimer.

Molecular function

Activator, DNA-binding

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