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Target
Application
Host
Type
Species Reactivity
Conjugate


TFR2

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Anti-TFR2 ProductsBackground
Anti-TFR2 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, IHC, ELISA
- Rabbit Anti-TfR2 Recombinant Antibody (clone JG58-34) (MRO-1523-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
-
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: IF, IHC-P, FC
- Mouse Anti-NHP TFR2 Recombinant Antibody (clone OTI2B4) (VS-1024-XY502)
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- Species Reactivity: Human, Mouse, Non-human primate, Rat
- Type: Mouse IgG2a
- Application: WB, IF, FC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Protein class
Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Transporters
Predicted location
Membrane
Single cell type specificity
Group enriched (Hepatocytes, Erythroid cells)
Immune cell specificity
Group enriched (basophil, eosinophil)
Cell line specificity
Group enriched (HEL, HMC-1, K-562)
Interaction
Homodimer.
Molecular function
Receptor
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