TIF1B
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For Research Use Only. Not For Clinical Use.
Background
Tripartite motif containing 28 (TRIM28) mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zincbinding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.