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TIMM22
Loading...Anti-TIMM22 Products
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB
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- Anti-TIMM22 Immunohistochemistry Kit (VS-0525-XY7262)
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- Species Reactivity: Human
- Target: TIMM22
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Protein class
Disease related genes, Human disease related genes
Predicted location
Membrane
Single cell type specificity
Low cell type specificity
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Low cell line specificity
Interaction
Component of the TIM22 complex, whose core is composed of TIMM22, associated with peripheral protein FXC1/TIMM10B and the 70 kDa heterohexamer (PubMed:14726512, PubMed:27265872). In most cases, the 70 kDa complex is composed of TIMM9 and TIMM10 (TIMM10A or TIMM10B) (PubMed:14726512). A small fraction of the 70 kDa complex is composed of TIMM8 (TIMM8A/DDP1 or TIMM8B/DDP2) and TIMM13 (PubMed:14726512). The TIM22 complex also contains AGK and TIMM29 (PubMed:27718247, PubMed:28712724, PubMed:28712726). Interacts directly with TIMM9, TIMM10A and FXC1/TIMM10B (PubMed:14726512). Interacts (when oxidized) with TIMM29; interaction is direct (PubMed:27718247).
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