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TIMM22

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Anti-TIMM22 Products

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For Research Use Only. Not For Clinical Use.


Background

Protein class

Disease related genes, Human disease related genes

Predicted location

Membrane

Single cell type specificity

Low cell type specificity

Immune cell specificity

Immune cell enriched (basophil)

Cell line specificity

Low cell line specificity

Interaction

Component of the TIM22 complex, whose core is composed of TIMM22, associated with peripheral protein FXC1/TIMM10B and the 70 kDa heterohexamer (PubMed:14726512, PubMed:27265872). In most cases, the 70 kDa complex is composed of TIMM9 and TIMM10 (TIMM10A or TIMM10B) (PubMed:14726512). A small fraction of the 70 kDa complex is composed of TIMM8 (TIMM8A/DDP1 or TIMM8B/DDP2) and TIMM13 (PubMed:14726512). The TIM22 complex also contains AGK and TIMM29 (PubMed:27718247, PubMed:28712724, PubMed:28712726). Interacts directly with TIMM9, TIMM10A and FXC1/TIMM10B (PubMed:14726512). Interacts (when oxidized) with TIMM29; interaction is direct (PubMed:27718247).

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