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TKT R438W
Loading...Anti-TKT R438W Products
- Human Anti-TKT R438W Recombinant Soluble TCR (clone MEL21) (scTCR-1176YC-S(P))
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- Epitope: AMFWSVPTV
- MHC: HLA-A*02:01
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- Recombinant Human Anti-TKT R438W Soluble TCR (MEL21) (C-Cys) (VS-0622-YF5173)
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- Epitope: AMFWSVPTV
- MHC: HLA-A*02:01
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- Recombinant Human Anti-TKT R438W Soluble TCR (MEL21) (KIH) (VS-0622-YF7881)
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- Epitope: AMFWSVPTV
- MHC: HLA-A*02:01
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For Research Use Only. Not For Clinical Use.
T cell immunity directed against tumor-encoded amino acid substitutions occurs in some melanoma patients. This implicates missense mutations as a source of patient-specific neoantigens. TKT R438W is characterized as subdominant antigens as T cell immunity required peptide vaccination and these neoantigens are processed and presented from endogenously expressed protein.