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TLK1

Anti-TLK1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Heterodimerizes with TLK2. Interacts with ASF1A and ASF1B.

Molecular function

Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase

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