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TLR10

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For Research Use Only. Not For Clinical Use.


Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Protein class

CD markers, Enzymes, Plasma proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (B-cells, Microglial cells, dendritic cells)

Immune cell specificity

Group enriched (memory B-cell, naive B-cell)

Cell line specificity

Group enriched (Daudi, REH, U-698)

Interaction

Binds MYD88 via their respective TIR domains (By similarity). Homodimer (Potential).

Molecular function

Hydrolase, Receptor

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