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TLR10
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Protein class
CD markers, Enzymes, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (B-cells, Microglial cells, dendritic cells)
Immune cell specificity
Group enriched (memory B-cell, naive B-cell)
Cell line specificity
Group enriched (Daudi, REH, U-698)
Interaction
Binds MYD88 via their respective TIR domains (By similarity). Homodimer (Potential).
Molecular function
Hydrolase, Receptor
More Types Infomation
Related Signaling Pathways
NLR Signaling Pathway
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, ELISA
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For Research Use Only. Not For Clinical Use.