


Anti-TLR8 Recombinant Antibody Products

Anti-TLR8 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, FC, ICC, IF, IHC, Dot
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- Species Reactivity: Human
- Application: FC, IHC-P, WB
- Anti-TLR8 Immunohistochemistry Kit (VS-0525-XY7313)
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- Species Reactivity: Human
- Target: TLR8
- Application: IHC
- Anti-Mouse TLR8 Immunohistochemistry Kit (VS-0525-XY7314)
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- Species Reactivity: Human, Mouse, Rabbit
- Target: TLR8
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Creative Biolabs proudly presents its cutting-edge anti-TLR8 recombinant antibody products, meticulously developed to empower global research and pharmaceutical development. These high-quality antibodies are engineered for unparalleled specificity and consistency, serving as indispensable tools for advanced immunological research, target validation, and the development of innovative therapeutic strategies.
TLR8: A Pivotal Target for Immunomodulatory Therapy
Toll-like Receptor 8 (TLR8) is a crucial innate immune receptor located within endosomes, primarily responsible for sensing single-stranded RNA (ssRNA) derived from pathogens. Extensive research has elucidated its structural configurations, including agonist- and antagonist-induced dimer formations, proposing detailed functional mechanisms. Given its critical role in antiviral immunity and modulating inflammatory responses, TLR8 represents a pivotal target for understanding disease pathogenesis and developing novel immunomodulatory and anti-infective therapies.
Alternative Names
Toll-like receptor 8; toll like receptor 8; CD288; hIMD98.
Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
CD markers
Membrane
Group enriched (Kupffer cells, monocytes, Macrophages)
Group enriched (neutrophil, classical monocyte, non-classical monocyte, intermediate monocyte, myeloid DC)
Not detected
Homodimer (PubMed:23520111, PubMed:25599397, PubMed:26929371, PubMed:29155428). Interacts with MYD88 via their respective TIR domains (Probable). Interacts with UNC93B1 (By similarity). Interacts with BTK (PubMed:17932028). Interacts with SMPDL3B (By similarity).
Receptor
Anti-TLR8 rAb Products
Our anti-TLR8 recombinant antibody products are meticulously engineered to offer superior performance for your research needs. Produced using advanced recombinant technology, these antibodies boast exceptional specificity, high purity, and remarkable batch-to-batch consistency. This ensures reliable and reproducible results across diverse applications, making them an ideal choice for accurate target identification, precise cellular detection, and robust functional assays in immunological studies.
Table 1. Featured anti-TLR8 recombinant antibody products at Creative Biolabs.
Cat. No. | Product Name | Target Species | Host Species | Applications |
MOB-1646z | Mouse Anti-TLR8 Recombinant Antibody (clone 28H8) | Human | Mouse IgG1, κ | WB, FC, ICC, IF, IHC, DB |
MOB-2061CT | Recombinant Mouse anti-Human TLR8 Monoclonal antibody (55D254) | Human | Mouse | FC, IHC-P, WB |
Creative Quality Control
At Creative Biolabs, we implement rigorous, multi-faceted quality control measures to evaluate our anti-TLR8 recombinant antibody products utilizing state-of-the-art analytical techniques. Each batch is extensively validated for specificity, purity, affinity, and biological activity through methods such as SDS-PAGE, SEC-HPLC, ELISA, and functional assays. This stringent approach guarantees uncompromised quality, superior performance, and absolute reliability for our global customers.
Customer Reviews

Recombinant Mouse anti-Human TLR8 Monoclonal antibody (55D254) (MOB-2061CT)

Mouse Anti-TLR8 Recombinant Antibody (clone 28H8) (MOB-1646z)

Mouse Anti-TLR8 Recombinant Antibody (clone 28H8) (MOB-1646z)
rAb Production
The manufacturing of our anti-TLR8 recombinant antibody products adheres to highly optimized protocols, leveraging cutting-edge recombinant expression platforms, primarily in mammalian cell systems. This meticulous approach ensures the generation of antibodies with correct folding and essential post-translational modifications, which are critical for their biological functionality. Our scalable production capabilities and stringent in-process controls are designed to deliver consistent supply and superior quality, meeting the exacting demands of advanced scientific research and preclinical validation.
Featured Anti-TLR8 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-TLR8 recombinant antibody production.
Fig.2 Gram-scale anti-TLR8 recombinant antibody production.
rAb Modalities
Creative Biolabs offers anti-TLR8 recombinant antibodies in various modalities, including different host species and conjugation options. This versatility ensures that our antibodies can be seamlessly integrated into a wide array of experimental designs and detection platforms.
Fig.3 Full-length anti-TLR8 recombinant antibody production and modalities.
TLR8-Targeted Drug Information
Table 2. Public drug targeting TLR8.
Research phase | Company | Classification | Indications | Details |
Zhejiang University (Originator) | Preclinical |
Cancer Immunotherapy Liposomes Monoclonal Antibodies |
Cancer, breast Cancer, solid tumor |
|
Universitaet Bern (Originator) | Preclinical |
Cancer Immunotherapy Cancer Vaccines Nanoparticles Single-stranded oligoribonucleotide (RNA) Toxins Virus-Like Particle Vaccines |
Cancer | |
Altimmune (Originator) | Preclinical |
Cancer Immunotherapy Cancer Vaccines Peptide Vaccines |
Cancer, colorectal Cancer, solid tumor |
|
Korea University (Originator) | Preclinical | MicroRNA | Atopic dermatitis | |
Sungkyunkwan University (Originator) | Biological Testing |
Coronavirus Vaccines Nanoparticles Polypeptides, from 41 AA Recombinant proteins Recombinant Vaccines |
Coronavirus acute respiratory syndrome | |
Sungkyunkwan University (Originator) | Biological Testing |
Cancer Immunotherapy Cancer Vaccines Nanoparticles Peptides Peptide Vaccines |
Cancer | |
Sichuan University (SCU) (Originator) | Biological Testing |
Cancer Immunotherapy Cancer Vaccines Extracellular Vesicles Vaccine Adjuvants |
Cancer, breast | |
Cero Therapeutics (Originator) | Biological Testing |
Cancer Immunotherapy Cytotoxic T Lymphocytes (CTLs) TCR-Modified T Cells |
Cancer, head and neck (squamous cell carcinoma) |
(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)
As a trusted leader in antibody development, Creative Biolabs is dedicated to providing high-quality solutions that propel scientific discovery. Our anti-TLR8 recombinant antibody products are a testament to our commitment to innovation and excellence. We invite you to explore how these advanced tools can benefit your research and therapeutic development efforts. For customized solutions or to discuss your specific project needs, please do not hesitate to get in touch with us.