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TMIGD2

Anti-TMIGD2 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgM, κ
- Application: WB, ELISA, IF, IP
- Mouse anti Human TMIGD2 Polyclonal antibody (MOB-0409ZL)
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- Species Reactivity: Human
- Application: WB
- Rabbit anti Human TMIGD2 Polyclonal antibody (MOB-0410ZL)
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- Species Reactivity: Human, Mouse
- Application: ELISA, WB, IHC
- Mouse Anti-TMIGD2 Recombinant Antibody (clone CBL997) (NEUT-2045CQ)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: Block, CyTOF, FC
- Anti-TMIGD2 Immunohistochemistry Kit (VS-0525-XY7335)
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- Species Reactivity: Human
- Target: TMIGD2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Group enriched (NK-cells, dendritic cells, T-cells)
Immune cell specificity
Immune cell enhanced (MAIT T-cell)
Cell line specificity
Group enriched (BEWO, HEL, MOLT-4)
Interaction
May form homophilic interactions that could regulate cell-cell interaction. Interacts with CACNB2, DST, MIA and NCKIPSD. Interacts with HHLA2.
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