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TPH1
Anti-TPH1 Recombinant Antibody Products
- Rabbit Anti-TPH1 Recombinant Antibody (clone CBACN-562) (MRO-1534-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP, FC
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, IP, FC
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- AbPlus™ Anti-TPH1 Magnetic Beads (VS-0724-YC353) (VS-0724-YC353)
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- Target: TPH1
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009]
Protein class
Enzymes, FDA approved drug targets, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Enteroendocrine cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HL-60)
Interaction
Homotetramer.
Molecular function
Monooxygenase, Oxidoreductase
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