+ Filter
Loading...
TRIM34
Anti-TRIM34 Recombinant Antibody Products
CompareCan't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (B-cells, Gastric mucus-secreting cells, Squamous epithelial cells, T-cells, Basal squamous epithelial cells, Macrophages)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (BEWO, SK-BR-3)
Interaction
Homotrimer. Interacts (via the B30. 2/SPRY domain) with HIV-1 capsid complexes (PubMed:17156811). Interacts (via B-box and SPRY domain) with TRIM5 (PubMed:21680743, PubMed:17156811).
More Types Infomation