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TRIM69

Anti-TRIM69 Products
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Early spermatids, Late spermatids)
Immune cell specificity
Immune cell enriched (T-reg)
Cell line specificity
Cell line enhanced (Karpas-707, U-266/70, U-266/84)
Interaction
Interacts with PML.
Molecular function
Transferase
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