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TRMU
Loading...Anti-TRMU Products
- Mouse Anti-NHP TRMU Recombinant Antibody (clone OTI2A4) (VS-1024-XY515)
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- Species Reactivity: Dog, Human, Mouse, Non-human primate
- Type: Mouse IgG2a
- Application: WB, ICC
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More Infomation
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For Research Use Only. Not For Clinical Use.
This nuclear gene encodes a mitochondrial tRNA-modifying enzyme. The encoded protein catalyzes the 2-thiolation of uridine on the wobble positions of tRNA(Lys), tRNA(Glu), and tRNA(Gln), resulting in the formation of 5-taurinomethyl-2-thiouridine moieties. Mutations in this gene may cause transient infantile liver failure. Polymorphisms in this gene may also influence the severity of deafness caused by mitochondrial 12S ribosomal RNA mutations. Alternative splicing results in multiple transcript variants.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Molecular function
RNA-binding, Transferase, tRNA-binding
More Types Infomation