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TSC22D1
Loading...Anti-TSC22D1 Recombinant Antibody Products
- AbPlus™ Anti-TSC22D1 Magnetic Beads (VS-0724-YC1077) (VS-0724-YC1077)
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- Target: TSC22D1
- Target Species: Human, Mouse
- Application: IP, Protein Purification
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- Anti-TSC22D1 Immunohistochemistry Kit (VS-0325-XY2378)
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- Species Reactivity: Human, Mouse, Rat
- Target: TSC22D1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids)
Immune cell specificity
Immune cell enhanced (basophil)
Cell line specificity
Cell line enhanced (HEL)
Interaction
Homodimer or heterodimer. Can form a heterodimer with TSC22D4.
Molecular function
Repressor
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