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For Research Use Only. Not For Clinical Use.


This is one of two neighboring genes encoding similar proteins that each contain two rhodanese domains. The encoded protein is localized to the mitochondria and catalyzes the conversion of thiosulfate and cyanide to thiocyanate and sulfite. In addition, the protein interacts with 5S ribosomal RNA and facilitates its import into the mitochondria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Distal enterocytes, Paneth cells, Hepatocytes, Proximal enterocytes, Proximal tubular cells, Undifferentiated cells)

Immune cell specificity

Immune cell enhanced (myeloid DC)

Cell line specificity

Cell line enhanced (OE19)

Interaction

Monomer.

Molecular function

RNA-binding, Transferase

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