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For Research Use Only. Not For Clinical Use.
Intracellular
Cell type enhanced (Inhibitory neurons, Excitatory neurons, Astrocytes, Oligodendrocytes, Oligodendrocyte precursor cells)
Group enriched (eosinophil, basophil)
Cell line enhanced (HMC-1)
Component of a phosphatidylinositol 4-kinase (PI4K) complex, composed of PI4KA, EFR3 (EFR3A or EFR3B), TTC7 (TTC7A or TTC7B) and FAM126 (FAM126A or FAM126B) (PubMed:23229899). Interacts with PI4KA, interaction is direct (PubMed:26571211). Interacts with EFR3 (EFR3A or EFR3B), interaction is direct (PubMed:26571211). Interacts with FAM126 (FAM126A or FAM126B), interaction is direct (PubMed:26571211). Association with the PI4K complex is strongly reduced by TMEM150A (PubMed:25608530).