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TTC7B

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Inhibitory neurons, Excitatory neurons, Astrocytes, Oligodendrocytes, Oligodendrocyte precursor cells)

Immune cell specificity

Group enriched (eosinophil, basophil)

Cell line specificity

Cell line enhanced (HMC-1)

Interaction

Component of a phosphatidylinositol 4-kinase (PI4K) complex, composed of PI4KA, EFR3 (EFR3A or EFR3B), TTC7 (TTC7A or TTC7B) and FAM126 (FAM126A or FAM126B) (PubMed:23229899). Interacts with PI4KA, interaction is direct (PubMed:26571211). Interacts with EFR3 (EFR3A or EFR3B), interaction is direct (PubMed:26571211). Interacts with FAM126 (FAM126A or FAM126B), interaction is direct (PubMed:26571211). Association with the PI4K complex is strongly reduced by TMEM150A (PubMed:25608530).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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