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UBA2
Loading...Anti-UBA2 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, IHC, ELISA
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- Rabbit Anti-UBA2 Recombinant Antibody (clone JM66-53) (MRO-1362-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IP
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- Mouse Anti-NHP UBA2 Recombinant Antibody (clone OTI4A3) (VS-1024-XY523)
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- Species Reactivity: Dog, Human, Non-human primate, Rat
- Type: Mouse IgG2a
- Application: WB, IHC, ICC
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- Anti-UBA2 Immunohistochemistry Kit (VS-0325-XY2411)
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- Species Reactivity: Human, Mouse, Rat
- Target: UBA2
- Application: IHC
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- Anti-Mouse UBA2 Immunohistochemistry Kit (VS-0525-XY7680)
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- Species Reactivity: Human, Mouse, Rat, Canine, Monkey
- Target: UBA2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins
Protein class
Metabolic proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Sertoli cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
Molecular function
Transferase
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