USH1C

Antibody Magnetic Beads AbPlus Recombinant Antibody Products Formats

Anti-USH1C Recombinant Antibody Products

Mouse Anti-USH1C Recombinant Antibody (clone 8G10) (MOB-2449z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, ELISA, IP
Compare

Recombinant Mouse anti-Human USH1C Monoclonal antibody (EML1164) (MOB-2150CT)
- Species Reactivity: Human
- Application: WB
Compare

AbPlus™ Anti-USH1C Magnetic Beads (VS-0724-YC1412) (VS-0724-YC1412)
- Target: USH1C
- Target Species: Human
- Application: IP, Protein Purification
Compare

Rabbit Anti-USH1C Recombinant Antibody (clone DS3800AB) (MOR-3800)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IP
Compare

More Infomation

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.

This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Protein class

Cancer-related genes, Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Proximal enterocytes, Paneth cells, Proximal tubular cells, Distal enterocytes, Muller glia cells, Undifferentiated cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (CACO-2, HeLa, OE19)

Interaction

Part of the IMAC/intermicrovillar adhesion complex/intermicrovillar tip-link complex composed of ANKS4B, MYO7B, USH1C, CDHR2 and CDHR5 (Probable). Part of a complex composed of USH1C, USH1G and MYO7A (PubMed:21709241). Interacts with F-actin (By similarity). Interacts with USH2A (PubMed:16301216). Interacts with SLC4A7 (PubMed:16301216). Interacts (via PDZ1 domain) with the C-terminus of USHBP1 (PubMed:11311560). Interacts (via N-terminus and PDZ 2 domain) with CDH23 (PubMed:19297620). Interacts with USH1G (PubMed:12588794, PubMed:20142502). Interacts with MYO7B (PubMed:24725409, PubMed:26812017). Interacts with CDHR2 and CDHR5; may mediate their interaction with MYO7B at the microvilli tip (PubMed:24725409, PubMed:26812017). Interacts (via PDZ 1 domain) with ANKS4B (PubMed:26812018, PubMed:26812017). Interacts (via PDZ 1 domain) with DOCK4 (PubMed:16464467).

More Types Infomation