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UTF1
The protein encoded by this gene is a leucine zipper-containing transcriptional coactivator that may link the upstream activator ATF2 with the basal transcription complex. The encoded protein is closely associated with chromatin and is required for the proper differentiation of embryonic carcinoma and embryonic stem cells. Found nearly exclusively in pluripotent cells, this protein can also serve as a transcriptional repressor. [provided by RefSeq, Nov 2015]
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Group enriched (Langerhans cells, Spermatogonia)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (NTERA-2, RPMI-8226)
Interaction
Binds to the N-terminal region of ATF2. Associates with the TFIID complex through interaction with TBP.
Molecular function
Activator
More Types Infomation
- Mouse Anti-UTF1 Recombinant Antibody (clone E0-F4) (MRO-1566-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG2b
- Application: WB, IF
- Rabbit Anti-UTF1 Polyclonal Antibody (MRO-2262-CN) (MRO-2262-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
- Mouse Anti-UTF1 Recombinant Antibody (clone 5B6) (VS3-QX1227)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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For Research Use Only. Not For Clinical Use.