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UTF1

Anti-UTF1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is a leucine zipper-containing transcriptional coactivator that may link the upstream activator ATF2 with the basal transcription complex. The encoded protein is closely associated with chromatin and is required for the proper differentiation of embryonic carcinoma and embryonic stem cells. Found nearly exclusively in pluripotent cells, this protein can also serve as a transcriptional repressor. [provided by RefSeq, Nov 2015]
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Group enriched (Langerhans cells, Spermatogonia)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (NTERA-2, RPMI-8226)

Interaction

Binds to the N-terminal region of ATF2. Associates with the TFIID complex through interaction with TBP.

Molecular function

Activator

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