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VDAC2
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective
Protein class
Transporters
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with hexokinases (By similarity). Interacts with ARMC12 in a TBC1D21-dependent manner (By similarity). Interacts with KLC3 (By similarity). Interacts with SPATA33 (By similarity). Interacts with PPP3CC in a SPATA33-dependent manner (By similarity).
Molecular function
Porin
More Types Infomation
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, ELISA, ICC, IF
- Chicken Anti-VDAC2 Polyclonal IgY (BRD-0773MZ)
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- Species Reactivity: Bovine, Human, Mouse, Rabbit, Rat
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.