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VIPR2

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For Research Use Only. Not For Clinical Use.


Background

This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. [provided by RefSeq, Aug 2011]
Protein class

G-protein coupled receptors

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Oligodendrocyte precursor cells, Rod photoreceptor cells, Muller glia cells, dendritic cells, Excitatory neurons)

Immune cell specificity

Immune cell enriched (plasmacytoid DC)

Cell line specificity

Cell line enhanced (HeLa, HMC-1, MOLT-4, U-266/70)

Molecular function

G-protein coupled receptor, Receptor, Transducer

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