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VPS28
Anti-VPS28 Recombinant Antibody Products
- Mouse Anti-NHP VPS28 Recombinant Antibody (clone OTI1A8) (VS-1024-XY541)
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- Species Reactivity: Dog, Human, Mouse, Non-human primate, Rat
- Type: Mouse IgG1
- Application: WB, IHC, IF
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IP
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- Chicken Anti-VPS28 Polyclonal IgY (BRD-0626MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein subunit of the ESCRT-I complex (endosomal complexes required for transport), which functions in the transport and sorting of proteins into subcellular vesicles. This complex can also be hijacked to facilitate the budding of enveloped viruses from the cell membrane. Alternative splicing results in multiple transcript variants encoding different isoforms.
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (ASC diff, SH-SY5Y)
Interaction
Component of the ESCRT-I complex (endosomal sorting complex required for transport I) which consists of TSG101, VPS28, a VPS37 protein (VPS37A to -D) and MVB12A or MVB12B in a 1:1:1:1 stoichiometry (PubMed:14505570, PubMed:18005716). Interacts with TSG101, VPS37B, VPS37C, MVB12A and MVB12B (PubMed:14505570, PubMed:15218037, PubMed:18005716). Component of an ESCRT-I complex (endosomal sorting complex required for transport I) which consists of TSG101, VPS28, VPS37A and UBAP1 in a 1:1:1:1 stoichiometry (PubMed:14505570, PubMed:21757351, PubMed:30929741). Interacts WITH VPS36; the interaction mediates the association with the ESCRT-II complex. Interacts with SNF8 and VPS25 (PubMed:18539118). Interacts with CEP55 (PubMed:17853893).
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