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WFDC2

Anti-WFDC2 Products
- Recombinant Human Anti-human WFDC2 Antibody (MHH-1048)
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: Neut, IF, FuncS
- Recombinant Anti-human WFDC2 Antibody (MOB-1048)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, IP, FuncS
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- Species Reactivity: Human
- Application: WB
- Rabbit Anti-WFDC2 Recombinant Antibody (clone JF62-09) (MRO-0727-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP, FC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, CLIA, RIA, IHC, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, CLIA, RIA, IHC, WB
- Recombinant Anti-human WFDC2 Antibody Fab Fragment (MOB-1048-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, Neut, FuncS
- Recombinant Anti-human WFDC2 Antibody scFv Fragment (MOB-1048-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, IP, FuncS
- Recombinant Human Anti-human WFDC2 Antibody Fab Fragment (MHH-1048-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: RIA, ELISA, FuncS
- Recombinant Human Anti-human WFDC2 Antibody scFv Fragment (MHH-1048-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, Neut, FuncS
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC-P, FC, IP
- Anti-WFDC2 Immunohistochemistry Kit (VS-0525-XY7908)
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- Species Reactivity: Human
- Target: WFDC2
- Application: IHC
- Anti-Mouse WFDC2 Immunohistochemistry Kit (VS-0525-XY7909)
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- Species Reactivity: Human, Mouse
- Target: WFDC2
- Application: IHC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: FC, ICC, WB
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
Protein class
Cancer-related genes
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Club cells, Glandular and luminal cells, Basal respiratory cells, Urothelial cells, Endometrial ciliated cells, Respiratory ciliated cells, Collecting duct cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (A-431, CAPAN-2, EFO-21, HaCaT, RPTEC TERT1)
Interaction
Homotrimer; disulfide-linked.
Molecular function
Aspartic protease inhibitor, Protease inhibitor, Serine protease inhibitor, Thiol protease inhibitor
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